Reuters: Science News: Mouse body clock study offers clues to possible jet lag cure

Reuters: Science News Reuters.com is your source for breaking news, business, financial and investing news, including personal finance and stocks. Reuters is the leading global provider of news, financial information and technology solutions to the world's media, financial institutions, businesses and individuals. // via fulltextrssfeed.com

Want new traffic sources? Download a copy of our complimentary eBook today, and read about sources that most marketers are not aware of. From our sponsors

Mouse body clock study offers clues to possible jet lag cure Aug 29th 2013, 16:22 LONDON | Thu Aug 29, 2013 12:22pm EDT LONDON (Reuters) - Scientists have found a genetic mechanism in mice that hampers their body clock's ability to adjust to changes in patterns of light and dark, and say their results could someday lead to the development of drugs to combat jet lag. Researchers from Britain's Oxford University and from the Swiss drug firm Roche used mice to analyze patterns of genes in an area of the brain called the suprachiasmatic nuclei (SCN) - which in mammals pulls every cell in the body into the same biological rhythm. They found that one molecule, called SIK1, is key to how the mice responded to changes in light cycles. When the scientists blocked the activity of SIK1, the mice recovered faster from disturbances in their daily light and dark cycle that had been designed to induce a form of mouse jet lag. If the corresponding mechanism can be found and similarly blocked in humans, jet lag may become a thing of the past, the researchers said in their study, published online in the journal Cell on Thursday. "We're still several years away from a cure for jet lag, but understanding the mechanisms that generate and regulate our circadian clock gives us targets to develop drugs to help bring our bodies in tune with the solar cycle," said Russell Foster, director of Oxford's sleep and circadian neuroscience institute. He said such drugs could also have broader potential value, including for people with mental illnesses where sleep disturbances are common. (Reporting by Kate Kelland; Editing by Sonya Hepinstall) Link this Share this Digg this Email Reprints

You are receiving this email because you subscribed to this feed at blogtrottr.com. If you no longer wish to receive these emails, you can unsubscribe from this feed, or manage all your subscriptions