Thursday, May 31, 2012

Reuters: Science News: Scientists unlock gene secrets of opium poppy drug

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Scientists unlock gene secrets of opium poppy drug
May 31st 2012, 18:04

By Ben Hirschler

LONDON | Thu May 31, 2012 2:04pm EDT

LONDON (Reuters) - Scientists have unravelled exactly how opium poppies produce a non-addictive compound that can both suppress coughs and kill tumor cells, paving the way for improved production of the medicine.

Opium poppies, the source of illicit heroin, are also important for producing medical painkillers such as morphine and codeine, along with noscapine, which has been used for decades as a cough suppressant.

More recently, researchers have found noscapine is also a potent anti-cancer agent, prompting clinical tests into its role in fighting blood cancer.

The discovery that a cluster of 10 genes is responsible for the synthesis of noscapine inside the poppies means plant breeders can now develop high-yielding varieties. It may also help scientists in future produce the drug in factories.

The findings by researchers at the University of York and GlaxoSmithKline were published on Thursday in the journal Science.

British-based GSK is a leading producer of opium-based ingredients, supplying around 20 percent of the world's medicinal opiate needs from poppies grown by farmers in Tasmania.

The fact that all the genes associated with noscapine are clustered together makes life much easier for plant breeders who can use the information to develop high-yielding commercial noscapine poppies.

In contrast to illegal opium production in countries like Afghanistan, where harvesting is done by hand by lancing poppy heads, commercial pharmaceutical production is highly mechanized, with farmers using modern combine harvesters.

That makes commercial poppy cultivation a cost-effective process, even though most medicines today are produced by chemical synthesis or biotechnology.

"The poppy plant is very efficient at producing these compounds," said Ian Graham, director of the Centre for Novel Agricultural Products at York.

Working back from a strain of poppies producing high levels of noscapine, Graham and colleagues followed the trail of genes linked to the chemical to home in on the cluster of 10 specific genes central to production of the compound.

The cluster of genes, all of which are inherited together, is the most complex ever found in plants.

Noscapine was first discovered in the early 19th century and has been used to suppress coughs since the 1950s, but interest in the compound has grown since 1998 when scientists demonstrated that it acts as a potent anti-tumor agent.

It functions in a similar way to Taxol, a cancer drug originally isolated from the bark of the Pacific yew tree and commercialized by Bristol-Myers Squibb.

Cougar Biotechnology, now part of Johnson & Johnson, has been studying noscapine as a treatment for multiple myeloma, a type of cancer affecting the plasma cells in bone marrow.

(Reporting by Ben Hirschler; Editing by Will Waterman)

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Reuters: Science News: Paralysed rats walk again in Swiss lab study

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Paralysed rats walk again in Swiss lab study
May 31st 2012, 18:01

By Chris Wickham

LONDON | Thu May 31, 2012 2:01pm EDT

LONDON (Reuters) - Scientists in Switzerland have restored full movement to rats paralysed by spinal cord injuries in a study that might eventually be used in people with similar injuries.

Gregoire Courtine and his team at Ecole Polytechnique Federale de Lausanne saw rats with severe paralysis walking and running again after a couple of weeks following a combination of electrical and chemical stimulation of the spinal cord together with robotic support.

"Our rats are not only voluntarily initiating a walking gait, but they are soon sprinting, climbing up stairs and avoiding obstacles," said Courtine, whose results from the five-year study will be published in the journal Science on Friday.

Courtine is quick to point out that it remains unclear if a similar technique could help people with spinal cord damage but he adds the technique does hint at new ways of treating paralysis.

Other scientists agree.

"This is ground-breaking research and offers great hope for the future of restoring function to spinal injured patients," said Elizabeth Bradbury, a Medical Research Council senior fellow at King's College London.

But Bradbury notes that very few human spinal cord injuries are the result of a direct cut through the cord, which is what the rats had. Human injuries are most often the result of bruising or compression and it is unclear if the technique could be translated across to this type of injury.

It is also unclear if this kind of electro-chemical "kick-start" could help a spinal cord that has been damaged for a long time, with complications like scar tissue, holes and where a large number of nerve cells and fibres have died or degenerated.

Nevertheless, Courtine's work does demonstrate a way of encouraging and increasing the innate ability of the spinal cord to repair itself, a quality known as neuroplasticity.

Other attempts to repair spinal cords have focused on stem cell therapy, although Geron, the world's leading embryonic stem cell company, last year closed its pioneering work in the field.

The brain and spinal cord can adapt and recover from small injuries but until now that ability was far too limited to overcome severe damage. This new study proves that recovery from severe injury is possible if the dormant spinal column is "woken up".

Norman Saunders, a neuroscientist at the University of Melbourne in Australia, said in an emailed statement reacting to the study that although it remains to be seen whether the technique can be translated to people, "it looks more promising than previously proposed treatments for spinal cord injury".

Bryce Vissel, head of the Neurodegenerative Diseases Research Laboratory at the Garvan Institute of Medical Research in Sydney, said the study "suggests we are on the edge of a truly profound advance in modern medicine: the prospect of repairing the spinal cord after injury".

Courtine hopes to start human trials in a year or two at Balgrist University Hospital Spinal Cord Injury Centre in Zurich.

"Our rats have become athletes when just weeks before they were completely paralysed," he said. "I am talking about 100 percent recuperation of voluntary movement."

(Editing by Ben Hirschler and Alessandra Rizzo)

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Reuters: Science News: Drug bans hamper brain research, says neuroscientist

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Drug bans hamper brain research, says neuroscientist
May 31st 2012, 09:04

By Kate Kelland

LONDON | Thu May 31, 2012 5:04am EDT

LONDON (Reuters) - Bans on drugs like ecstasy, magic mushrooms and LSD have hampered scientific research on the brain and stalled the progress of medicine as much as George Bush's ban on stem cell research did, a leading British drug expert said on Thursday.

David Nutt, a professor of neuropsychopharmacology at Imperial College London and a former chief adviser on drugs to the British government, said the international prohibition of psychedelics and other mind-altering drugs over the past half century has had damaging and "perverse" consequences.

"When a drug becomes illegal, conducting experimental research on it becomes almost impossible," Nutt told reporters at a briefing in London ahead of the publication of his new book "Drugs - without the hot air".

He compared the situation with that in stem cell research under former U.S. President George W. Bush, who banned any new embryonic stem cell studies from 2001 to 2009 - a move many scientists consider held the field back for years.

Nutt said the problem with the current approach to drugs policy globally, which is centered on the banning of substances thought to be most harmful, "is that we lose sight of the fact that these drugs may well give us insights into areas of science which need to be explored and they also may give us new opportunities for treatment."

"Almost all the drugs which are of interest in terms of brain phenomena like consciousness, perception, mood, psychosis - drugs like psychedelics, ketamine, cannabis, magic mushrooms, MDMA - are currently illegal. So there's almost no (scientific)work in this field," Nutt said.

Nutt last year conducted a small human trial to study the effects of psilocybin, the active ingredient in magic mushrooms, on the brain.

Contrary to scientists' expectations, the study found psilocybin doesn't increase but rather suppresses activity in areas of the brain linked to depression, suggesting the drug might be a useful treatment for the debilitating condition.

Nutt said he was forced to "jump through hundreds of hoops" to be able to conduct the study, having to comply with a level of complex, expensive and time-consuming security and regulation that would put most scientists off.

WHAT DRUGS ARE AND WHAT THEY DO

The professor, who was sacked in 2009 in a high-profile row with the British government after he compared the risks of smoking cannabis with those of riding a horse, said he was driven to write the book in the hope of improving understanding of drugs - both legal and illegal, medicinal and recreational.

"There is almost no one in society who doesn't take drugs of some sort. The choices you make in your drug-taking are driven by a complex mixture of fashion, habit, availability and advertising," he said.

"If we understand drugs more, and have a more rational approach to them, we will actually end up knowing more about how to deal with drug harms."

Published on Thursday, the book seeks to explore the science of what a drug is and how it works.

It discusses whether the "war on drugs" did more harm than good - Nutt thinks it did.

And it explores why Britain's Queen Victoria took cannabis - apparently her physician J.R. Reynolds wrote a paper in the Lancet medical journal saying that "when pure and administered carefully, it (cannabis) is one of the most valuable medicines we possess". He prescribed it to the monarch to help her with period pains and after childbirth.

The book also has chapters on why people take drugs now, how harmful they are, where and whether the danger lines should be drawn between legal drugs like tobacco and alcohol, and illegal ones like cannabis and magic mushrooms.

Nutt doesn't dispute that drugs are harmful, but he takes issue with what he says are un-scientific decisions to ban one, like cannabis, while allowing another, like alcohol, to be freely and cheaply available on supermarket shelves.

"Drugs are drugs. They may differ in terms of their brain effects, but fundamentally they are all psychotropic agents," he said. "And it's arbitrary whether we choose to keep alcohol legal and ban cannabis, or make tobacco legal and ban ecstasy. Those are not scientific decisions they are political, moral and maybe even religious decisions."

(Reporting by Kate Kelland, editing by Paul Casciato)

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Wednesday, May 30, 2012

Reuters: Science News: SpaceX Dragon capsule heading back to Earth

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SpaceX Dragon capsule heading back to Earth
May 31st 2012, 04:05

The SpaceX Dragon commercial cargo craft is seen docked to the Harmony node of the International Space Station with the Japanese Kibo Laboratory module in the foreground and the earth in the background in this image from NASA TV May 26, 2012. REUTERS/NASA TV

1 of 3. The SpaceX Dragon commercial cargo craft is seen docked to the Harmony node of the International Space Station with the Japanese Kibo Laboratory module in the foreground and the earth in the background in this image from NASA TV May 26, 2012.

Credit: Reuters/NASA TV

By Irene Klotz

CAPE CANAVERAL, Florida | Thu May 31, 2012 12:05am EDT

CAPE CANAVERAL, Florida (Reuters) - Space Exploration Technologies' Dragon spaceship was poised to wrap up a pioneering test flight, the first by a private company to the International Space Station, and head back to Earth on Thursday.

Dragon became the first privately owned vehicle to reach the $100 billion research complex, a project of 15 countries, on Friday when astronauts used the station's robot arm to pluck it from orbit and latch it onto a berthing port as the spacecraft sailed about 250 miles above the planet.

The bell-shaped capsule, which was partly financed by NASA, was scheduled to be detached from the station at 4:05 a.m. EDT (0805 GMT) on Thursday and released from the station's crane about 90 minutes later. Splashdown in the Pacific Ocean about 564 miles southwest of Los Angeles is expected at 11:44 a.m. EDT (1544 GMT).

Space Exploration Technologies, or SpaceX, successful recovered a Dragon capsule from orbit during a previous test flight in December 2010.

"We've done it once, but it's still a very challenging phase of flight," SpaceX mission director John Couluris told reporters on Wednesday.

The United States has been without its own transportation to the station since the space shuttles were retired last year. Rather than build and operate a government-owned replacement, NASA is investing in companies such as SpaceX with the intention of buying rides for its cargo - and eventually astronauts - on commercial vehicles, a far cheaper alternative.

"The ability to get to (the) space station on our first time, to not only rendezvous but then to berth, transfer cargo and depart safely are major mission objectives. We would call that mission alone a success," Couluris said.

The successful trial run is expected to clear SpaceX to begin working off its 12-flight, $1.6 billion NASA contract to fly cargo to the station.

A second commercial freighter, built by Orbital Sciences Corp is expected to debut this year.

"Our plans are to carry out a test launch in the August-September time frame and the demonstration mission - same as what SpaceX impressively just did - in the November-December time frame," Orbital spokesman Barry Beneski wrote in an email to Reuters.

Orbital has a similar contract to deliver space station cargo, valued at $1.9 billion.

After leaving the space station, SpaceX's Dragon capsule is expected to fire its steering jets to leave orbit and begin its plunge through the atmosphere.

Recovery ships owned by American Marine Corp of Los Angeles, will be standing by to pick up the capsule and bring it back to the Port of Los Angeles, a trip that should take two or three days.

From there, Dragon will be taken to a SpaceX processing facility in McGregor, Texas, and unloaded and inspected.

The company's last test will be to see if it can speedily return some equipment coming back from the station to NASA within 48 hours, a practice run for ferrying home precious science samples when Dragon begins regular cargo hauls.

The rest of the 1,300 lbs (590 kg) of gear returning on Dragon is due to be sent to NASA within two weeks, said flight director Holly Ridings.

"Because this is a test flight, specifically the program made sure that there's not anything coming home that we couldn't afford to not get back," she said.

"I know it's a really important capability to prove for NASA and for the space station program as we go forward, since this vehicle has the unique capability to return cargo," Ridings said.

The only vehicles currently flying to the station that return to Earth are Russian Soyuz spacecraft, which primarily are used to transport crew and have little room for cargo. The other freighters are discarded and burn up in the atmosphere.

(Editing by Jane Sutton and Lisa Shumaker)

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Reuters: Science News: FAA clears Virgin Galactic spaceship for test flights

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FAA clears Virgin Galactic spaceship for test flights
May 30th 2012, 23:14

By Irene Klotz

CAPE CANAVERAL, Florida | Wed May 30, 2012 7:14pm EDT

CAPE CANAVERAL, Florida (Reuters) - The U.S. Federal Aviation Administration has cleared SpaceShipTwo, a commercial six-passenger spacecraft owned by Virgin Galactic, to begin rocket-powered suborbital test flights, the company said on Wednesday.

SpaceShipTwo manufacturer Scaled Composites of Mojave, California, received a one-year experimental launch permit on May 23 for test flights beyond the atmosphere, FAA spokesman Hank Price said.

The six-passenger, two-pilot spacecraft is based on the prototype SpaceShipOne, also built by Scaled, which clinched the $10 million Ansari X Prize in 2004 for the first privately funded human spaceflights.

SpaceShipOne made three suborbital hops beyond the atmosphere, each with a solo pilot aboard, ultimately reaching an altitude of nearly 70 miles above Earth. SpaceShipOne is now on display at the Smithsonian Institution's National Air and Space Museum in Washington.

Virgin Galactic is owned by British billionaire Richard Branson's Virgin Group and Aabar Investments PJS. Branson hired SpaceShipOne designer Burt Rutan, who has since retired from Scaled, to create a fleet of spaceships for commercial use. Virgin Galactic has taken deposits from more than 500 people for rides, which cost $200,000.

Participants will experience a few minutes of weightlessness and see the curve of Earth set against the black sky of space. NASA's first two manned spaceflights in 1961, by Mercury astronauts Alan Shepard and Virgil "Gus" Grissom were suborbital flights.

Like SpaceShipOne, Virgin Galactic's SpaceShipTwo will be flown into the air beneath a carrier jet and released. Once separated, the spaceship's rocket engine will fire to blast it into the sky. SpaceShipTwo has completed 16 free flight tests.

The FAA permit will enable Scaled, now wholly owned by Northrop Grumman, to move on to rocket-powered flights, the first of which is expected toward the end of the year, Virgin Galactic said in a statement.

Company President George Whitesides called the permit an Â"important milestone "that positions the company Â"a major step closer to bringing our customers to space."

In addition to flying wealthy tourists, Scaled has signed contracts to fly researchers and science experiments.

The experimental permit allows Scaled to fly only its own test pilots, not passengers, Price said.

A date for the start of Virgin Galactic's commercial spaceflights has not yet been set.

(Editing by Jane Sutton and Anthony Boadle)

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Reuters: Science News: Fukushima quake, tsunami disturbed upper atmosphere: NASA

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Fukushima quake, tsunami disturbed upper atmosphere: NASA
May 30th 2012, 19:33

WASHINGTON | Wed May 30, 2012 3:33pm EDT

WASHINGTON (Reuters) - The massive earthquake and tsunami that hit Fukushima, Japan, last year wreaked havoc in the skies above as well, disturbing electrons in the upper atmosphere, NASA reported.

The waves of energy from the quake and tsunami that were so destructive on the ground reached into the ionosphere, a part of the upper atmosphere that stretches from about 50 to 500 miles above Earth's surface.

The ionosphere is the last, thinnest part of the atmosphere, where solar ultraviolet radiation breaks up molecules and leaves a haze of electrons and ions.

In images released on Friday, NASA showed how the earthly disturbances from the March 11, 2011, quake and tsunami were echoed in the movement of electrons far aloft. This movement was monitored by tracking the GPS signals between satellites and ground receivers.

Scientists have seen this phenomenon before, for tsunamis in Samoa in 2009 and Chile in 2010. The Japanese event, however, occurred in a region more closely monitored by a dense network of GPS receivers, NASA said in a statement.

Still images of the disturbance are online here. Video is available here

(Reporting by Deborah Zabarenko; Editing by Doina Chiacu)

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Reuters: Science News: Tomato genome project bears fruit

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Tomato genome project bears fruit
May 30th 2012, 17:02

By Kate Kelland

LONDON | Wed May 30, 2012 1:02pm EDT

LONDON (Reuters) - An international team of scientists has cracked the genetic code of the domesticated tomato and its wild ancestor, an achievement which should help breeders identify the genes needed to develop tastier and more nutritious varieties.

The full genome sequence of a tomato breed known as Heinz 1706, and a draft sequence for its closest wild relative Solanum pimpinellifolium, were published in the journal Nature on Wednesday.

Researchers who carried out the work said that together the sequences provide the most detailed look yet at the functional parts of the tomato genome and show order, orientation, types and relative positions of all of its 35,000 genes.

The sequences should help researchers find the links between certain tomato genes and the characteristics they determine, and will also extend scientists' understanding of how genetic and environmental factors affect the health of a crop.

"Tomatoes are one of the most important fruit crops in the world, both in terms of the volume that we eat and the vitamins, minerals and other phytochemicals that both fresh and processed tomato products provide to our diets," said Graham Seymour, a professor of biotechnology at Nottingham University, one of 300 scientists involved in the Tomato Genome Consortium (TGC).

TOMATOES ARE NOT THE ONLY FRUIT

The tomato is also a good model to investigate the process of fruit ripening, so understanding its genome should help reveal the molecular circuits that make fruits ripen and give them their health-promoting properties, the team said.

"For any characteristic of the tomato, whether it's taste, natural pest resistance or nutritional content, we've captured virtually all those genes," said James Giovannoni from the Boyce Thompson Institute for Plant Research at Cornell University, who was part of the U.S. tomato sequencing team.

Tomatoes represent a $2 billion market in the United States alone, while in Britain the market for tomatoes is worth around 625 million pounds ($980 million) a year.

The research also offers some insight into how the tomato and its relatives diversified and adapted to new environments over the years.

The scientists said the findings show the tomato genome expanded abruptly about 60 million years ago. Some of the genes generated during that expansion were involved in the development and control of ripening, making them particularly interesting to tomato breeders.

The TGC involved scientists in 14 countries including Argentina, China, France, Germany, India, Japan, South Korea, Britain, the United States and others.

Giovanni said the work has implications for other plant species.

Strawberries, apples, melons, bananas and other fleshy fruits share some characteristics with tomatoes, he explained, so knowledge about the genes involved in fruit ripening could potentially be applied to them, helping breeders and growers to improve food quality and cut costs.

"Now we can start asking a lot more interesting questions about fruit biology, disease resistance, root development and nutritional qualities," he said in a statement.

(Editing by Janet Lawrence)

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Tuesday, May 29, 2012

Reuters: Science News: Intelsat buys ride on new SpaceX heavy-lift rocket

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Intelsat buys ride on new SpaceX heavy-lift rocket
May 29th 2012, 21:24

By Irene Klotz

CAPE CANAVERAL, Florida | Tue May 29, 2012 5:24pm EDT

CAPE CANAVERAL, Florida (Reuters) - Intelsat Global Holdings S.A. will buy a ride for a future communications satellite on Space Exploration Technologies' planned heavy-lift rocket, the companies said on Tuesday.

The contract is the first for a Falcon Heavy rocket, which is being designed to carry more than twice as much as the Boeing-built Delta 4 Heavy launcher, which is currently the biggest rocket in the U.S. fleet.

Terms of the contract were not disclosed, but Space Exploration Technologies, or SpaceX, has said it expects to sell Falcon Heavy flights to commercial customers for about $100 million.

United Launch Alliance, a partnership of Boeing and Lockheed Martin that markets and flies Delta 4 and Atlas 5 rockets, does not disclose prices.

Luxembourg-based, privately held Intelsat currently operates 52 communications satellites and has plans to launch four more spacecraft this year, said company spokesman Alex Horwitz.

The contract with SpaceX is for one satellite launch, he added. A launch site and time frame for the flight were not disclosed.

Intelsat's launch will follow test flights of Falcon Heavy, a rocket based on the company's Falcon 9 rocket which last week launched a Dragon cargo capsule on a test flight to the International Space Station.

SpaceX, which is owned and operated by Internet entrepreneur Elon Musk, has a 12-flight, $1.6 billion contract with NASA to deliver cargo to and from the space station, which orbits about 240 miles above Earth.

Since the space shuttles were retired last year, the United States is dependent on partner countries in Europe, Japan and Russia to fly cargo and crew to the $100 billion outpost.

Falcon 9's launch manifest also includes more than two dozen flights for non-U.S. government and commercial customers, such as Iridium, Asia Satellite Telecommunications Co. and SES.

Falcon Heavy is expected to debut in 2013.

On May 18, Intelsat, the world's biggest operator of satellite services, filed with U.S. regulators to raise up to $1.75 billion in an initial public offering of its common stock. The company operated as an intergovernmental organization for more than 30 years before becoming a private firm in 2001.

Intelsat was purchased in 2008 by Serafina Acquisition Ltd, which is backed by private equity firm Silver Lake, among other funds.

Intelsat posted a net loss of $400 million on revenue of $2.6 billion for the year ending December 31, according to the regulatory filing.

SpaceX, which was founded in 2002, is owned by Musk, other managers and employees, with minority investments from Founders Fund, Draper Fisher Jurvetson, and Valor Equity Partners.

(Editing by Jane Sutton and Kenneth Barry)

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Friday, May 25, 2012

Reuters: Science News: SpaceX capsule docks at space station, opens new era

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SpaceX capsule docks at space station, opens new era
May 26th 2012, 03:07

The SpaceX Falcon 9 test rocket lifts off from Space Launch Complex 40 at the Cape Canaveral Air Force Station in Cape Canaveral, Florida, May 22, 2012. The unmanned rocket owned by privately held Space Exploration Technologies blasted off from Cape Canaveral on Tuesday for a mission designed to be the first commercial flight to the International Space Station. The 178-foot (54-meter) tall Falcon 9 rocket lifted off at 3:44 a.m. (0744 GMT) from a refurbished launch pad just south of where NASA launched its now-retired space shuttles. REUTERS/Pierre DuCharme

1 of 3. The SpaceX Falcon 9 test rocket lifts off from Space Launch Complex 40 at the Cape Canaveral Air Force Station in Cape Canaveral, Florida, May 22, 2012. The unmanned rocket owned by privately held Space Exploration Technologies blasted off from Cape Canaveral on Tuesday for a mission designed to be the first commercial flight to the International Space Station. The 178-foot (54-meter) tall Falcon 9 rocket lifted off at 3:44 a.m. (0744 GMT) from a refurbished launch pad just south of where NASA launched its now-retired space shuttles.

Credit: Reuters/Pierre DuCharme

By Irene Klotz

CAPE CANAVERAL, Florida | Fri May 25, 2012 11:07pm EDT

CAPE CANAVERAL, Florida (Reuters) - Astronauts aboard the International Space Station captured the SpaceX Dragon cargo ship and guided the privately owned craft into a docking berth on Friday, opening a new chapter in the U.S. space program.

The unmanned capsule was the first commercial spaceship to reach the orbital outpost.

"This really is the beginning of a new era in commercial spaceflight," said Alan Lindenmoyer, who manages NASA's commercial space transportation programs.

Using the station's 58-foot long (17.7-meter) robotic crane, NASA astronaut Don Pettit snared Dragon at 9:56 a.m. EDT as the two spacecraft zoomed 250 miles over northwest Australia at 17,500 miles per hour.

"Â"It looks like we've got us a dragon by the tail," Pettit radioed to NASA Mission Control in Houston.

The capsule, built and operated by Space Exploration Technologies, or SpaceX, is the first of two new commercial freighters NASA will use to ferry cargo to the $100 billion space station following the retirement of its space shuttles last year. Rather than building and flying its own ships to the station, the agency is hiring private companies to do the work.

The Dragon capsule is carrying about 1,200 pounds (544 kg) of food, water, clothing and supplies for the station crew, who were scheduled to open the hatch on Saturday.

The spaceship will be repacked with more than 1,300 pounds (590 kg) of equipment to come back to Earth and depart the station on May 31. It would splash down in the Pacific Ocean off the coast of southern California later that day.

Â""As a country we should be very proud," NASA's space station program manager Mike Suffredini told reporters after the station crew attached Dragon to the Harmony connecting node shortly after noon EDT.

"We've taken a capability that this agency has nurtured for many, many years and combined that with a different thought process in the design and development of spacecraft," Suffredini said.

The United States plans to use a similar process to buy commercial flight services for its astronauts as well, breaking Russia's monopoly on flying crews to the station.

"I don't have words enough to express the level of excitement and elation that we feel here at SpaceX," company founder and chief executive Elon Musk said after the docking.

"There's just so much that could have gone wrong and it went right. It's just a fantastic day," he said.

Musk said he got a congratulatory call from President Barack Obama after Dragon reached orbit on its second and most likely final test flight. "Caller ID was blocked, so at first I thought it was a telemarketer," Musk quipped in a Twitter message.

LASER GLITCH

The cone-shaped capsule blasted off aboard a SpaceX Falcon 9 rocket from Cape Canaveral Air Force Station on Tuesday.

After a successful pass by the station on Thursday to test its navigation and communications systems, Dragon proceeded at a snail's pace on Friday, stopping, starting and occasionally retreating to make sure it could be controlled.

At one point, the SpaceX ground operations team in Hawthorne, California, halted Dragon to adjust the capsule's laser imaging system, which it uses to see the station.

Sensors were picking up stray reflections from the station's Japanese module, said NASA mission commentator Josh Byerly.

Dragon ended up using just one of its two laser imaging systems for the final approach to the station, a bit dicey because a failure would have triggered an automatic abort.

But one eye and a pair of thermal imagers was all Dragon needed to position itself 30 feet beneath the station and within arm's reach of the robotic crane that would haul it up for berthing.

PRIVATE DELIVERIES

Dragon's successful test flight will clear SpaceX to begin its 12-flight, $1.6 billion contract with NASA to fly cargo to and from the station.

A second freighter being developed by Orbital Sciences Corp is expected to debut later this year. Orbital holds a second NASA cargo delivery contract worth $1.9 billion.

The Obama administration is pushing Congress to embrace similar partnership arrangement for commercial space taxis to fly astronauts as well.

Legislators last year halved Obama's request for space taxi design work to $406 million. Proposed spending plans for the year beginning October 1 would cut the White House's $830 million request to no more than $525 million.

The Dragon docking marked a major step for the budding role of private enterprise in space travel.

"I think this really is going to be recognized as a significantly historical step forward in space travel, so I hope we're the first of many to come," Musk told reporters.

(Reporting by Irene Klotz; Editing by Anthony Boadle)

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Reuters: Science News: Corrected: Gevo starts up first new plant, shares jump

Reuters: Science News
Reuters.com is your source for breaking news, business, financial and investing news, including personal finance and stocks. Reuters is the leading global provider of news, financial information and technology solutions to the world's media, financial institutions, businesses and individuals. // via fulltextrssfeed.com
Corrected: Gevo starts up first new plant, shares jump
May 25th 2012, 20:57

Fri May 25, 2012 4:57pm EDT

(Reuters) - Gevo Inc started production at a converted ethanol plant in Minnesota, bringing on line the world's first commercial-scale facility to make advanced biofuels and renewable chemicals. Shares rose more than 9 percent.

Gevo said it had flipped the switch on the plant, which will produce isobutanol from corn starch, on Wednesday and it expects to ship the first rail cars of the chemical to its customer Sasol around the end of June.

Sasol plans to the sell the isobutanol into the solvents and specialty chemicals markets, although the organic compound can also be used as an alternative to gasoline.

Chief Executive Officer Patrick Gruber told Reuters the company would begin production slowly at the new facility located in Luverne, Minnesota and planned to increase output to about 1 million gallons per month around the end of the year.

In addition to the isobutanol sales, Gevo will sell the corn by-products into the animal feed market.

Gevo retrofitted the ethanol plant to use its own yeast and fermentation technology to produce isobutanol. The company is currently engaged in a legal dispute with Butamax, a joint venture of BP Plc and DuPont over the technology.

The company is planning to start another larger facility in Redfield, South Dakota next year.

Investors, who have been wary of shares in the new advanced biofuels makers, welcomed the news pushing its share price up 9.5 percent to $5.86 per share on the Nasdaq.

Analysts have attributed some of that market wariness to the company's plan to raise an estimated $75 million to $100 million around mid-year.

"We still have to raise money this year, and it's question of when we pull that trigger," Gruber said.

(This story is filed to correct paragraph 3 to show Sasol plans to sell the isobutanol into the solvents and specialty chemicals markets instead of use it as a feedstock in its chemical products in the May 24 story)

(Reporting By Matt Daily; Editing by Leslie Gevirtz)

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Reuters: Science News: SpaceX Dragon capsule docks with space station

Reuters: Science News
Reuters.com is your source for breaking news, business, financial and investing news, including personal finance and stocks. Reuters is the leading global provider of news, financial information and technology solutions to the world's media, financial institutions, businesses and individuals. // via fulltextrssfeed.com
SpaceX Dragon capsule docks with space station
May 25th 2012, 16:34

The SpaceX Falcon 9 test rocket lifts off from Space Launch Complex 40 at the Cape Canaveral Air Force Station in Cape Canaveral, Florida, May 22, 2012. REUTERS/Pierre DuCharme

1 of 6. The SpaceX Falcon 9 test rocket lifts off from Space Launch Complex 40 at the Cape Canaveral Air Force Station in Cape Canaveral, Florida, May 22, 2012.

Credit: Reuters/Pierre DuCharme

By Irene Klotz

CAPE CANAVERAL, Florida | Fri May 25, 2012 12:34pm EDT

CAPE CANAVERAL, Florida (Reuters) - Astronauts aboard the International Space Station captured Space Exploration Technologies' Dragon cargo ship and guided it into a berth on Friday, docking the first privately owned vehicle to reach the orbital outpost.

Using the station's 58-foot long (17.7-meter) robotic crane, NASA astronaut Don Pettit snared Dragon at 9:56 a.m. EDT (1356 GMT) as the two spacecraft zoomed 250 miles over northwest Australia at 17,500 miles per hour.

"It looks like we've got us a dragon by the tail," Pettit radioed to NASA Mission Control in Houston.

The capsule, built and operated by Space Exploration Technologies, or SpaceX, is the first of two new commercial freighters NASA will use to fly cargo to the $100 billion outpost following the retirement of the space shuttles last year.

The United States plans to buy commercial flight services for its astronauts as well, breaking Russia's monopoly on flying crews to the station.

Dragon blasted off aboard a SpaceX Falcon 9 rocket from Cape Canaveral Air Force Station on Tuesday. The space station crew anchored it into the station's Harmony connecting node around noon on Friday.

After a successful pass by the station on Thursday to test its navigation and communications systems, Dragon proceeded at a snail's pace on Friday, stopping, starting and occasionally retreating to make sure it could be controlled.

At one point, the SpaceX ground operations team in Hawthorne, California, halted Dragon to adjust the capsule's laser imaging system, which it uses to see the station. Sensors were picking up stray reflections from the station's Japanese module, said NASA mission commentator Josh Byerly.

Dragon ended up using just one of its two laser imaging systems for the final approach to the station, a bit dicey because a failure would have triggered an automatic abort.

But one eye was all Dragon needed to position itself 30 feet beneath the station and within arm's reach of the robotic crane that would haul it up for berthing.

"Â"Congratulations on a wonderful capture," astronaut Megan Behnken radioed to the station crew from Mission Control. "Â"You've made a lot of folks happy down here, over in Hawthorne and right here in Houston. Great job, guys."

SpaceX founder and chief designer Elon Musk said he got a congratulatory call from President Barack Obama after Dragon reached orbit on its second and most likely final test flight.

Â""Caller ID was blocked, so at first I thought it was a telemarketer," Musk wrote in a Twitter message.

DRAGON DELIVERS

The Dragon capsule is carrying about 1,200 pounds (544 kg) of food, water, clothing and supplies for the station crew. It will be repacked with more than 1,300 pounds (590 kg) of equipment to come back to Earth and depart the station on May 31.

It would splash down in the Pacific Ocean off the coast of southern California later that day.

Dragon's successful test flight will clear SpaceX to begin working off its 12-flight, $1.6 billion contract with NASA to fly cargo to and from the station.

A second freighter being developed by Orbital Sciences Corp is expected to debut later this year. Orbital holds a second NASA cargo delivery contract worth $1.9 billion.

The Obama administration is pushing Congress to embrace similar partnership arrangement for commercial space taxis to fly astronauts as well.

Legislators last year halved Obama's request for space taxi design work to $406 million. Proposed spending plans for the year beginning October 1 would cut the White House's $830 million request to no more than $525 million.

(Reporting by Irene Klotz; Editing by Anthony Boadle)

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Reuters: Science News: Astronauts snare SpaceX Dragon capsule: NASA

Reuters: Science News
Reuters.com is your source for breaking news, business, financial and investing news, including personal finance and stocks. Reuters is the leading global provider of news, financial information and technology solutions to the world's media, financial institutions, businesses and individuals. // via fulltextrssfeed.com
Astronauts snare SpaceX Dragon capsule: NASA
May 25th 2012, 14:15

1 of 3. The SpaceX Falcon 9 test rocket lifts off from Space Launch Complex 40 at the Cape Canaveral Air Force Station in Cape Canaveral, Florida, May 22, 2012. The unmanned rocket owned by privately held Space Exploration Technologies blasted off from Cape Canaveral on Tuesday for a mission designed to be the first commercial flight to the International Space Station. The 178-foot (54-meter) tall Falcon 9 rocket lifted off at 3:44 a.m. (0744 GMT) from a refurbished launch pad just south of where NASA launched its now-retired space shuttles.

Credit: Reuters/Pierre DuCharme

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Reuters: Science News: Corrected: Decision time on site for giant radio telescope

Reuters: Science News
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Corrected: Decision time on site for giant radio telescope
May 25th 2012, 09:24

By Chris Wickham

LONDON | Fri May 25, 2012 5:24am EDT

LONDON (Reuters) - The location of a huge radio telescope strong enough to detect extraterrestrial life in the far reaches of the universe could be settled on Friday when the group in charge of the project meets in the Netherlands.

When completed in 2024 the "Square Kilometer Array" (SKA) will be made up of 3,000 dishes, each 15 meters wide, together with many more antennae, that will stretch over 3,000 km (1,864 miles).

Scanning the sky 10,000 times faster and with 50 times the sensitivity of any other telescope, it will be used to study the origins of the universe and will be able to detect weak signals that could indicate the presence of extraterrestrial life.

A joint bid between Australia and New Zealand to host the telescope is pitted against South Africa for a $2 billion project that will bestow an economic boost and major scientific prestige on the winner.

The lobbying has been intense and at times acrimonious, with the Australians raising concerns about the security of such an expensive project in South Africa, which suffers from high rates of violent crime. South Africa has accused the other side of dirty tricks and selectively leaking data to boost its bid in what are supposed to be secret deliberations.

The project could now be split between the two bidders. In March, a science panel gave a marginal preference to South Africa but after intense lobbying from both bidders the decision was delayed and a group of experts was set up to examine the scientific and cost implications of a split location.

That group will report back to the consortium on Friday but scientists say a split location would almost certainly add to the bill.

Radio telescopes work best in remote locations away from interference from other radio signals, hence the decision to site this one in the more sparsely-populated southern hemisphere.

MORE THAN SCIENTIFIC EYE CANDY

The SKA is more than just a scientific bauble for the winner. Global tech companies are already earmarking development funds linked to the project, which will rely on computing technology that does not even exist yet to process the flood of data it will collect. Scientists estimate that the SKA will need processing power equivalent to several million of today's fastest computers.

International Business Machines Corp and Astron, the Netherlands institute for radio astronomy, announced in April a 33 million euro ($42 million), five-year deal to develop extremely fast computer systems with low power requirements for the SKA project.

"If you take the current global daily Internet traffic and multiply it by two, you are in the range of the data set that the Square Kilometer Array radio telescope will be collecting every day," said IBM Researcher Ton Engbersen at the announcement of the deal.

Other companies that have signed partnership agreements with the project include Nokia-Siemens, BAE Systems PLC, Cisco Systems Inc and Selex Galileo, a UK unit of Italian group Finmeccanica SpA.

The engineering and computing challenges are significant, not least the provision of power to run the array and the supercomputers in such a remote location.

It is in overcoming those challenges that the leaders of the project argue could lead to untold spin-offs for industry. They point to Wi-Fi technology as one of the best known commercial applications to come from radio astronomy, for instance.

The first phase of construction is set to start in 2016, and by 2019 about 10 percent of the array should be built, extending some 100 km from the telescope's core. Expansion to 3,000 km should be complete by 2023 and the project will be fully up and running the following year.

ANSWERS TO BIG QUESTIONS

In an interview with Reuters, the leaders of the project said they hope the array will help to answer some of the biggest questions about the formation and make-up of the universe.

"For me, one of the most exciting questions is what is the universe made of," said John Womersley, Chair of the Board of Directors of the SKA organization. "We know that 5 pct of universe is made of atoms but what about the dark matter and other stuff that makes up 95 pct of the universe?

"Connecting to discoveries from the Large Hadron Collider, we will get a consistent picture of what the universe is made of."

The Large Hadron Collider is the world's largest and highest-energy particle accelerator and is testing some of the most basic theories in physics by smashing particle beams together to simulate the conditions in the universe a fraction of a second after the Big Bang.

Michiel van Haarlem, Director General of the group, said the telescope's capabilities will expand over time.

"In stage one, finding out about the first stars and galaxies that formed in the universe, pulsars and gravitational radiation. Then in the second stage the role of magnetic fields in the formation of galaxies and looking for SETI (Search for Extraterrestrial Life) type things."

The Britain-based consortium behind the telescope includes Canada, China, Italy, the Netherlands, the United Kingdom as well as Australia, New Zealand and South Africa.

(This story has been corrected to show that Germany is not a member of the SKA organization but New Zealand is. Germany was a member of the founding board for the project, which carried out preparatory work.)

($1 = 0.7947 euros)

(Editing by Myra MacDonald)

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